Paradoxical Reaction to Golimumab: Tumor Necrosis Factor a Inhibitor Inducing Psoriasis Pustulosa
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چکیده
منابع مشابه
Paradoxical Reaction to Golimumab: Tumor Necrosis Factor α Inhibitor Inducing Psoriasis Pustulosa
IMPORTANCE Golimumab is a human monoclonal antibody, used for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. Adverse reactions are increasing with this class of medication (tumor necrosis factor α inhibitors). OBSERVATIONS The authors present a case of a female patient who presented with psoriasis pustulosa after the use of golimumab for rheumatoid arthritis. CONCLUSI...
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• Golimumab is the first human monoclonal antibody to tumor necrosis factor (TNF) administered monthly by subcutaneous injection (pre-filled syringe or pre-filled pen, auto-injector). • The drug is approved by the U.S. Food and Drug Administration and by the European Medicines Agency for the treatment of severe/moderate active forms of Rheumatoid arthritis, psoriatic arthritis, and ankylosing s...
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UNLABELLED Rheumatoid arthritis is one of the commonest autoimmune diseases. It is a chronic, progressive, systemic inflammatory disorder affecting the synovial joints and typically producing symmetrical arthritis. If left untreated, it leads to joint destruction and thus deformity and disability.In the recent years, advances in molecular biology have led to a variety of new treatment approache...
متن کاملParadoxical response to disseminated non-tuberculosis mycobacteriosis treatment in a patient receiving tumor necrosis factor-a inhibitor: a case report
Background: Biological agents such as tumor necrosis factor-α inhibitors are known to cause mycobacterium infections. Here, we report a disseminated non-tuberculosis case caused by TNF-α inhibitor therapy and a probable paradoxical response to antimycobacterial therapy. Case presentation: A 68-year-old man with relapsing polychondritis was refractory to glucocorticoid therapy; adalimumab was th...
متن کاملParadoxical response to disseminated non-tuberculosis mycobacteriosis treatment in a patient receiving tumor necrosis factor-α inhibitor: a case report
BACKGROUND Biological agents such as tumor necrosis factor-α inhibitors are known to cause mycobacterium infections. Here, we report a disseminated non-tuberculosis case caused by TNF-α inhibitor therapy and a probable paradoxical response to antimycobacterial therapy. CASE PRESENTATION A 68-year-old man with relapsing polychondritis was refractory to glucocorticoid therapy; adalimumab was th...
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ژورنال
عنوان ژورنال: Case Reports in Dermatology
سال: 2013
ISSN: 1662-6567
DOI: 10.1159/000350930